中文名 | LY2183240 |
英文名 | 5-([1,1'-biphenyl]-4-ylmethyl)-N,N-dimethyl-1H-tetrazole-1-carboxamide |
别名 | 化合物LY2183240 5-([1,1'-联苯]-4-甲基)-N,N-二甲基-1H-四氮唑-1-甲酰胺 |
英文别名 | LY2183240 LY 2183240 LY-2183240 MN-25 N,N-dimethyl-5-[(4-phenylphenyl)methyl]tetrazole-1-carboxamide 5-(biphenyl-4-ylMethyl)-N,N-diMethyl-1H-tetrazole-1-carboxaMide 5-Biphenyl-4-ylmethyl-tetrazole-1-carboxylic acid dimethylamide 5-([1,1'-biphenyl]-4-ylmethyl)-N,N-dimethyl-1H-tetrazole-1-carboxamide 1H-Tetrazole-1-carboxamide, 5-([1,1′-biphenyl]-4-ylmethyl)-N,N-dimethyl- 5-[[(1,1'-BIPHENYL)-4-YL]METHYL]-N,N-DIMETHYL-1H-TETRAZOLE-1-CARBOXAMIDE |
CAS | 874902-19-9 |
化学式 | C17H17N5O |
分子量 | 307.35 |
密度 | 1.21 |
熔点 | 87-88℃ |
沸点 | 506.1±53.0 °C(Predicted) |
溶解度 | 溶于DMSO (大于25 mg/ml) 或乙醇 (高达15 mg/ml)。 |
酸度系数 | 0.01±0.10(Predicted) |
存储条件 | Sealed in dry,2-8°C |
稳定性 | 稳定1年的供应。乙醇的DMSO溶液可在-20 °C下储存长达1个月 |
外观 | 白色至灰白色固体。 |
颜色 | White |
靶点 | CUCQDDZYZNBQFE-KUNNFNOCSA-N |
危险品标志 | Xn - 有害物品 |
风险术语 | 22 - 吞食有害。 |
参考资料 展开查看 | 1: Köfalvi A, Lemos C, Martín-Moreno AM, Pinheiro BS, García-García L, Pozo MA, Valério-Fernandes Â, Beleza RO, Agostinho P, Rodrigues RJ, Pasquaré SJ, Cunha RA, de Ceballos ML. Stimulation of brain glucose uptake by cannabinoid CB(2) receptors and its therapeutic potential in Alzheimer's disease. Neuropharmacology. 2016 Mar 11. pii: S0028-3908(16)30087-9. doi: 10.1016/j.neuropharm.2016.03.015. [Epub ahead of print] PubMed PMID: 26976670. 2: Nicolussi S, Chicca A, Rau M, Rihs S, Soeberdt M, Abels C, Gertsch J. Correlating FAAH and anandamide cellular uptake inhibition using N-alkylcarbamate inhibitors: from ultrapotent to hyperpotent. Biochem Pharmacol. 2014 Dec 15;92(4):669-89. doi: 10.1016/j.bcp.2014.09.020. Epub 2014 Nov 4. PubMed PMID: 25283614. 3: Uchiyama N, Matsuda S, Kawamura M, Shimokawa Y, Kikura-Hanajiri R, Aritake K, Urade Y, Goda Y. Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products. Forensic Sci Int. 2014 Oct;243:1-13. doi: 10.1016/j.forsciint.2014.03.013. Epub 2014 Mar 27. PubMed PMID: 24769262. 4: Gonzalez-Islas C, Garcia-Bereguiain MA, Wenner P. Tonic and transient endocannabinoid regulation of AMPAergic miniature postsynaptic currents and homeostatic plasticity in embryonic motor networks. J Neurosci. 2012 Sep 26;32(39):13597-607. PubMed PMID: 23015449; PubMed Central PMCID: PMC3470113. 5: Powers MS, Barrenha GD, Mlinac NS, Barker EL, Chester JA. Effects of the |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.254 ml | 16.268 ml | 32.536 ml |
5 mM | 0.651 ml | 3.254 ml | 6.507 ml |
10 mM | 0.325 ml | 1.627 ml | 3.254 ml |
5 mM | 0.065 ml | 0.325 ml | 0.651 ml |
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